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KMID : 1001020110090010001
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Journal of Urologic Oncology
2011 Volume.9 No. 1 p.1 ~ p.8
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Lymphnode Assessment in Penile Cancer
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Kim Soo-Dong
Jung Se-Il
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Abstract
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This review aims to provide detailed, up-to-date information, based on rescent developments in our understanding and management of lymph node in penile squamous cell carcinoma(SCC). Herein we review the literature focusing on management strategies of both the clinically positive and negative groin after the successful management of the primary lesion. For low-risk patients(pTis, pTa, and pT1G1) without palpable lymph nodes and with good compliance, a surveillance strategy may be chosen. For all other patients without palpable lymph nodes(including intermediate risk pT1G2 disease), a modified bilateral lymphadenectomy is recommended. An alternative to this is a dynamic sentinel lymph node biopsy in specialized centres. All patients with histologically proven lymph node metastases should undergo radical inguinal lymphadenectomy. Pelvic lymph node dissection should be done in all patients with more than two metastatic inguinal lymph nodes. In case of fixed inguinal lymph nodes, neoadjuvant chemotherapy is recommended, followed by node resection. There is a consensus that the ultimate determination lymph nodes in penile cancer of survival in patients presenting with penile cancer rests with the detection and complete resection of nodal metastases. But, this resection carries with it a significant burden of morbidity that has led to develop protocols and techniques to maximize detection and minimize morbidity and unnecessary surgery.
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KEYWORD
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Penile neoplasm, Lymph node excision
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